Iferanserin mesylate| CAS#58754-46-4 | 5-HT2A receptor antagonist

MedKoo Cat#: 326940 | Name: Iferanserin mesylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iferanserin, also known as MSA-100; S-MPEC; VEN-309; SMPEC, is a selective serotonin receptor antagonist, is being studied for use in the treatment of hemorrhoid diseases.

Chemical Structure

Iferanserin mesylate

CAS#Iferanserin mesylate

Theoretical Analysis

MedKoo Cat#: 326940

Name: Iferanserin mesylate

CAS#: Iferanserin mesylate

Chemical Formula: C23H28N2O

Exact Mass: 348.2202

Molecular Weight: 348.49

Elemental Analysis: C, 79.27; H, 8.10; N, 8.04; O, 4.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

210350-29-1 (HCl) 951155-17-2 (S E isomer) 58754-46-4 (free base S EZ-isomers) Iferanserin mesylate

Synonym

Iferanserin mesylate; Iferanserin; MSA-100; MSA100; S-MPEC; VEN-309; VEN309; SMPEC.

IUPAC/Chemical Name

(E)-2'-(2-((2S)-1-Methyl-2-piperidyl)ethyl)cinnamanilide

InChi Key

UXIPFQUBOVWAQW-UEBLJOKOSA-N

InChi Code

InChI=1S/C23H28N2O/c1-25-18-8-7-12-21(25)16-15-20-11-5-6-13-22(20)24-23(26)17-14-19-9-3-2-4-10-19/h2-6,9-11,13-14,17,21H,7-8,12,15-16,18H2,1H3,(H,24,26)/b17-14+/t21-/m0/s1

SMILES Code

O=C(NC1=CC=CC=C1CC[C@H]2N(C)CCCC2)/C=C/C3=CC=CC=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 348.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Herold A, Dietrich J, Aitchison R. Intra-anal Iferanserin 10 mg BID for hemorrhoid disease: a prospective, randomized, double-blind, placebo-controlled trial. Clin Ther. 2012 Feb;34(2):329-40. doi: 10.1016/j.clinthera.2011.12.012. Epub 2012 Jan 11. PMID: 22244049.