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MedKoo Cat#: 326860 | Name: Eplivanserin hemifumarate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eplivanserin hemifumarate, also known as SR-46349 hemifumarate, is an inverse agonist on the serotonin receptor subtype 5-HT2A. In contrast to older sedating drugs acting on 5-HT2A receptors (e.g., mirtazapine, clozapine, risperidone), eplivanserin has practically no affinity to dopamine, histamine and adrenergic receptors.

Chemical Structure

Eplivanserin hemifumarate
Eplivanserin hemifumarate
CAS#130580-02-8 (fumarate)

Theoretical Analysis

MedKoo Cat#: 326860

Name: Eplivanserin hemifumarate

CAS#: 130580-02-8 (fumarate)

Chemical Formula: C42H46F2N4O8

Exact Mass: 0.0000

Molecular Weight: 772.85

Elemental Analysis: C, 65.27; H, 6.00; F, 4.92; N, 7.25; O, 16.56

Price and Availability

Size Price Availability Quantity
10mg USD 550.00 2 Weeks
50mg USD 1,350.00 2 Weeks
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Related CAS #
130579-75-8 (free base) 130580-02-8 (fumarate)
Synonym
SR-46349 fumarate; SR 46349 fumarate; SR46349 fumarate; Eplivanserin fumarate
IUPAC/Chemical Name
(1Z,2E)-1-(2-fluorophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one O-(2-(dimethylamino)ethyl) oxime fumarate (2:1)
InChi Key
RNLKLYQQDLHHBH-ABDBJYMXSA-N
InChi Code
InChI=1S/2C19H21FN2O2.C4H4O4/c2*1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15;5-3(6)1-2-4(7)8/h2*3-12,23H,13-14H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b2*12-9+,21-19-;2-1+
SMILES Code
OC1=CC=C(/C=C/C(C2=CC=CC=C2F)=N/OCCN(C)C)C=C1.O=C(O)/C=C/C(O)=O.OC3=CC=C(/C=C/C(C4=CC=CC=C4F)=N/OCCN(C)C)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 772.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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