Synonym
LY 97241; LY-97241; LY97241.
IUPAC/Chemical Name
Benzenebutanamine, N-ethyl-N-heptyl-4-nitro-
InChi Key
YTYATOMQOOFRNA-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H32N2O2/c1-3-5-6-7-9-16-20(4-2)17-10-8-11-18-12-14-19(15-13-18)21(22)23/h12-15H,3-11,16-17H2,1-2H3
SMILES Code
O=[N+](C1=CC=C(CCCCN(CC)CCCCCCC)C=C1)[O-]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
320.48
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Gessner G, Heinemann SH. Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241. Br J Pharmacol. 2003 Jan;138(1):161-71. PubMed PMID: 12522086; PubMed Central PMCID: PMC1573651.
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5: Suessbrich H, Schönherr R, Heinemann SH, Lang F, Busch AE. Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241. FEBS Lett. 1997 Sep 8;414(2):435-8. PubMed PMID: 9315735.
6: Zhang ZH, Steinberg MI. LY 97241 accelerates the apparent rate of inactivation of transient outward K+ current: characterization of open channel block. J Pharmacol Exp Ther. 1995 Jul;274(1):249-57. PubMed PMID: 7616405.
7: Walsh KB, Arena JP, Kwok WM, Freeman L, Kass RS. Delayed-rectifier potassium channel activity in isolated membrane patches of guinea pig ventricular myocytes. Am J Physiol. 1991 Apr;260(4 Pt 2):H1390-3. PubMed PMID: 1849375.
8: Arena JP, Kass RS. Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked. Mol Pharmacol. 1988 Jul;34(1):60-6. PubMed PMID: 2455861.
