LY 178002 | CAS#107889-32-7 | phospholipase A2 inhibitor

MedKoo Cat#: 525484 | Name: LY 178002

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY 178002 is a phospholipase A2 inhibitor. LY 178002 also inhibits leukotriene B4 production.

Chemical Structure

LY 178002

CAS#107889-32-7

Theoretical Analysis

MedKoo Cat#: 525484

Name: LY 178002

CAS#: 107889-32-7

Chemical Formula: C18H25NO2S

Exact Mass: 319.1606

Molecular Weight: 319.46

Elemental Analysis: C, 67.67; H, 7.89; N, 4.38; O, 10.02; S, 10.04

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LY 178002; LY178002; LY-178002.

IUPAC/Chemical Name

4-Thiazolidinone, 5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-

InChi Key

BUDGLLLMROWLOB-NTEUORMPSA-N

InChi Code

InChI=1S/C18H25NO2S/c1-17(2,3)12-7-11(9-14-16(21)19-10-22-14)8-13(15(12)20)18(4,5)6/h7-9,20H,10H2,1-6H3,(H,19,21)/b14-9+

SMILES Code

O=C1NCS/C1=C/C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 319.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Panetta JA, Clemens JA. Novel antioxidant therapy for cerebral ischemia-reperfusion injury. Ann N Y Acad Sci. 1994 Jun 17;723:239-45. PubMed PMID: 8030869. 2: Clemens JA, Ho PP, Panetta JA. LY178002 reduces rat brain damage after transient global forebrain ischemia. Stroke. 1991 Aug;22(8):1048-52. PubMed PMID: 1866752. 3: Panetta JA, Benslay DN, Phillips ML, Towner RD, Bertsch B, Wang L, Ho PP. The anti-inflammatory effects of LY178002 and LY256548. Agents Actions. 1989 Jun;27(3-4):300-2. PubMed PMID: 2508442.