Lombazole | CAS#60628-98-0 | Antimicrobial

MedKoo Cat#: 525450 | Name: Lombazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lombazole is an antimicrobial agent of the imidazole class.

Chemical Structure

Lombazole

CAS#60628-98-0

Theoretical Analysis

MedKoo Cat#: 525450

Name: Lombazole

CAS#: 60628-98-0

Chemical Formula: C22H17ClN2

Exact Mass: 344.1080

Molecular Weight: 344.84

Elemental Analysis: C, 76.63; H, 4.97; Cl, 10.28; N, 8.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lombazole; Bay h 6020; EINECS 262-337-1; Lombazole; Lombazolum.

IUPAC/Chemical Name

1-([1,1'-biphenyl]-4-yl(2-chlorophenyl)methyl)-1H-imidazole

InChi Key

DALSNPRWUFOYDT-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H17ClN2/c23-21-9-5-4-8-20(21)22(25-15-14-24-16-25)19-12-10-18(11-13-19)17-6-2-1-3-7-17/h1-16,22H

SMILES Code

ClC1=CC=CC=C1C(N2C=CN=C2)C3=CC=C(C4=CC=CC=C4)C=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 344.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Barug D, Bastiaanse HB, van Rossum JM, Kerkenaar A. Action of lombazole, and inhibitor of fungal ergosterol biosynthesis, on Staphylococcus epidermidis. Antimicrob Agents Chemother. 1986 Aug;30(2):238-44. PubMed PMID: 3532943; PubMed Central PMCID: PMC180526. 2: Barug D, de Groot K. Effect of the imidazole derivative lombazole on the ultrastructure of Staphylococcus epidermidis and Candida albicans. Antimicrob Agents Chemother. 1985 Nov;28(5):643-7. PubMed PMID: 3911878; PubMed Central PMCID: PMC176349.