JNJ-7925476 HCl is a novel triple monoamine uptake inhibitor. JNJ-7925476 Salt blocks the serotonin transporter (SERT), norepinephrine transporter (NET) and dopamine transporter (DAT) in the central nervous system. The ED(50) values for JNJ-7925476 occupancy of the SERT, NET, and DAT in rat brain were 0.18, 0.09 and 2.4 mg/kg, respectively.
MedKoo Cat#: 525411
Name: JNJ-7925476 HCl
CAS#: 109085-56-5
Chemical Formula: C20H20ClN
Exact Mass:
Molecular Weight: 309.84
Elemental Analysis: C, 77.53; H, 6.51; Cl, 11.44; N, 4.52
The following data is based on the product molecular weight 309.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
