Tryptophan | CAS#73-22-3 | essential amino aci

MedKoo Cat#: 596936 | Name: Tryptophan

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tryptophan is an essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Chemical Structure

Tryptophan

CAS#73-22-3

Theoretical Analysis

MedKoo Cat#: 596936

Name: Tryptophan

CAS#: 73-22-3

Chemical Formula: C11H12N2O2

Exact Mass: 204.0899

Molecular Weight: 204.22

Elemental Analysis: C, 64.69; H, 5.92; N, 13.72; O, 15.67

Price and Availability

Size	Price	Availability	Quantity
100g	USD 290.00
500g	USD 710.00
1kg	USD 1,080.00

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

Tryptophan; NSC 13119; NSC-13119; NSC13119; Ardeytropin; L-Tryptophane;

IUPAC/Chemical Name

tryptophan

InChi Key

QIVBCDIJIAJPQS-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)

SMILES Code

O=C(O)C(N)CC1=CNC2=C1C=CC=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 204.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ueda Y, Iwakura H, Bando M, Doi A, Ariyasu H, Inaba H, Morita S, Akamizu T. Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice. PLoS One. 2018 Jun 11;13(6):e0198762. doi: 10.1371/journal.pone.0198762. eCollection 2018. PubMed PMID: 29889885. 2: Badawy AA. Targeting tryptophan availability to tumors: the answer to immune escape? Immunol Cell Biol. 2018 Jun 10. doi: 10.1111/imcb.12168. [Epub ahead of print] PubMed PMID: 29888434. 3: Wu T, Xu J, Xie W, Yao Z, Yang H, Sun C, Li X. Pseudomonas aeruginosa L10: A Hydrocarbon-Degrading, Biosurfactant-Producing, and Plant-Growth-Promoting Endophytic Bacterium Isolated From a Reed (Phragmites australis). Front Microbiol. 2018 May 25;9:1087. doi: 10.3389/fmicb.2018.01087. eCollection 2018. PubMed PMID: 29887849; PubMed Central PMCID: PMC5980988. 4: Shima K, Kaeding N, Ogunsulire IM, Kaufhold I, Klinger M, Rupp J. Interferon-γ interferes with host cell metabolism during intracellular Chlamydia trachomatis infection. Cytokine. 2018 Jun 6. pii: S1043-4666(18)30237-0. doi: 10.1016/j.cyto.2018.05.039. [Epub ahead of print] PubMed PMID: 29885991. 5: Fuentes-Lemus E, Silva E, Barrias P, Aspee A, Escobar E, Lorentzen LG, Carroll L, Leinisch F, Davies MJ, López-Alarcón C. Aggregation of α- and β- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation. Free Radic Biol Med. 2018 Jun 7. pii: S0891-5849(18)31009-8. doi: 10.1016/j.freeradbiomed.2018.06.005. [Epub ahead of print] PubMed PMID: 29885785. 6: Pal S, Aute R, Sarkar P, Bose S, Deshmukh MV, Chattopadhyay A. Constrained dynamics of the sole tryptophan in the third intracellular loop of the serotonin(1)(A) receptor. Biophys Chem. 2018 Jun 1;240:34-41. doi: 10.1016/j.bpc.2018.05.008. [Epub ahead of print] PubMed PMID: 29885563. 7: Sun SL, Yang WL, Fang WW, Zhao YX, Guo L, Dai YJ. The plant growth-promoting rhizobacterium Variovorax boronicumulans CGMCC 4969 regulates the level of indole-3-acetic acid synthesized from indole-3-acetonitrile. Appl Environ Microbiol. 2018 Jun 8. pii: AEM.00298-18. doi: 10.1128/AEM.00298-18. [Epub ahead of print] PubMed PMID: 29884755. 8: Yu E, Papandreou C, Ruiz-Canela M, Guasch-Ferre M, Clish CB, Dennis C, Liang L, Corella D, Fitó M, Razquin C, Lapetra J, Estruch R, Ros E, Cofán M, Arós F, Toledo E, Serra-Majem L, Sorlí JV, Hu FB, Martinez-Gonzalez MA, Salas-Salvado J. Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case-Cohort Study. Clin Chem. 2018 Jun 8. pii: clinchem.2018.288720. doi: 10.1373/clinchem.2018.288720. [Epub ahead of print] PubMed PMID: 29884676. 9: Castro NSS, Laia CAT, Maiti BK, Cerqueira NMFSA, Moura I, Carepo MSP. Small phospho-donors phosphorylate MorR without inducing protein conformational changes. Biophys Chem. 2018 May 31;240:25-33. doi: 10.1016/j.bpc.2018.05.009. [Epub ahead of print] PubMed PMID: 29883882. 10: Miękus N, Olędzka I, Harshkova D, Liakh I, Plenis A, Kowalski P, Bączek T. Comparison of Three Extraction Approaches for the Isolation of Neurotransmitters from Rat Brain Samples. Int J Mol Sci. 2018 May 24;19(6). pii: E1560. doi: 10.3390/ijms19061560. PubMed PMID: 29882927. 11: Michaelian K. Homochirality through Photon-Induced Denaturing of RNA/DNA at the Origin of Life. Life (Basel). 2018 Jun 6;8(2). pii: E21. doi: 10.3390/life8020021. PubMed PMID: 29882802. 12: Liu Y, Hou H, Jiang X, Wang P, Dai X, Chen W, Gao L, Xia T. A WD40 Repeat Protein from Camellia sinensis Regulates Anthocyanin and Proanthocyanidin Accumulation through the Formation of MYB⁻bHLH⁻WD40 Ternary Complexes. Int J Mol Sci. 2018 Jun 6;19(6). pii: E1686. doi: 10.3390/ijms19061686. PubMed PMID: 29882778. 13: Youssef A, von Koschembahr A, Caillat S, Corre S, Galibert MD, Douki T. 6-Formylindolo[3,2-b]carbazole (FICZ) is a Very Minor Photoproduct of Tryptophan at Biologically Relevant Doses of UVB and Simulated Sunlight. Photochem Photobiol. 2018 Jun 8. doi: 10.1111/php.12950. [Epub ahead of print] PubMed PMID: 29882277. 14: Cao XY, Wang S, Tian SQ, Lou H, Kong YC, Yang ZJ, Liu JL. Spectroscopic and molecular modeling studies on the interactions of fluoranthene with bovine hemoglobin. Spectrochim Acta A Mol Biomol Spectrosc. 2018 May 30;203:301-307. doi: 10.1016/j.saa.2018.05.091. [Epub ahead of print] PubMed PMID: 29879645. 15: Yamashita-Kawanishi N, Sawanobori R, Matsumiya K, Uema A, Chambers JK, Uchida K, Shimakura H, Tsuzuki M, Chang CY, Chang HW, Haga T. Detection of felis catus papillomavirus type 3 and 4 DNA from squamous cell carcinoma cases of cats in Japan. J Vet Med Sci. 2018 Jun 5. doi: 10.1292/jvms.18-0089. [Epub ahead of print] PubMed PMID: 29877210. 16: Bolchi C, Bavo F, Regazzoni L, Pallavicini M. Preparation of enantiopure methionine, arginine, tryptophan, and proline benzyl esters in green ethers by Fischer-Speier reaction. Amino Acids. 2018 Jun 6. doi: 10.1007/s00726-018-2599-2. [Epub ahead of print] PubMed PMID: 29876689. 17: Peng J, Xiao Y, Li W, Yang Q, Tan L, Jia Y, Qu Y, Qian Z. Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy. Adv Sci (Weinh). 2018 Feb 26;5(5):1700891. doi: 10.1002/advs.201700891. eCollection 2018 May. PubMed PMID: 29876215; PubMed Central PMCID: PMC5979747. 18: DeLuca JA, Allred KF, Menon R, Riordan R, Weeks BR, Jayaraman A, Allred CD. Bisphenol-A alters microbiota metabolites derived from aromatic amino acids and worsens disease activity during colitis. Exp Biol Med (Maywood). 2018 Jan 1:1535370218782139. doi: 10.1177/1535370218782139. [Epub ahead of print] PubMed PMID: 29874946. 19: Gao J, Lv J, Wu H, Dai Y, Nasir M. Impacts of wheat straw addition on dissolved organic matter characteristics in cadmium-contaminated soils: Insights from fluorescence spectroscopy and environmental implications. Chemosphere. 2018 Feb;193:1027-1035. doi: 10.1016/j.chemosphere.2017.11.112. Epub 2017 Nov 21. PubMed PMID: 29874729. 20: McKay MJ, Martfeld AN, De Angelis AA, Opella SJ, Greathouse DV, Koeppe RE 2nd. Control of Transmembrane Helix Dynamics by Interfacial Tryptophan Residues. Biophys J. 2018 Jun 5;114(11):2617-2629. doi: 10.1016/j.bpj.2018.04.016. PubMed PMID: 29874612.