MedKoo Cat#: 525291 | Name: Ipsapirone hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ipsapirone, also known as BAY q 7821, is a new pyrimidinylpiperazine ligand potent and specific for 5-HT1A receptors. Ipsapirone hydrochloride has potential therapeutic use in affective disorders.

Chemical Structure

Ipsapirone hydrochloride
Ipsapirone hydrochloride
CAS#92589-98-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 525291

Name: Ipsapirone hydrochloride

CAS#: 92589-98-5 (HCl)

Chemical Formula: C19H24ClN5O3S

Exact Mass:

Molecular Weight: 437.94

Elemental Analysis: C, 52.11; H, 5.52; Cl, 8.10; N, 15.99; O, 10.96; S, 7.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Ipsapirone hydrochloride; Ipsapirone HCl; BAY q 7821; BAY q-7821; BAY q7821;
IUPAC/Chemical Name
1,2-Benzisothiazol-3(2H)-one, 2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, 1,1-dioxide, monohydrochloride
InChi Key
USDUGJXCPKBJTN-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H23N5O3S.ClH/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19;/h1-2,5-9H,3-4,10-15H2;1H
SMILES Code
O=C(C1=C2C=CC=C1)N(CCCCN3CCN(C4=NC=CC=N4)CC3)S2(=O)=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 437.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Druse MJ, Tajuddin NF, Gillespie RA, Le P. The effects of ethanol and the serotonin(1A) agonist ipsapirone on the expression of the serotonin(1A) receptor and several antiapoptotic proteins in fetal rhombencephalic neurons. Brain Res. 2006 May 30;1092(1):79-86. Epub 2006 May 9. PubMed PMID: 16687129. 2: Tajuddin NF, Orrico LA, Eriksen JL, Druse MJ. Effects of ethanol and ipsapirone on the development of midline raphe glial cells and astrocytes. Alcohol. 2003 Apr;29(3):157-64. PubMed PMID: 12798971. 3: Avgustinovich DF, Alekseyenko OV, Koryakina LA. Effects of chronic treatment with ipsapirone and buspirone on the C57BL/6J strain mice under social stress. Life Sci. 2003 Feb 14;72(13):1437-44. PubMed PMID: 12535712.