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MedKoo Cat#: 525258 | Name: Ethybenztropine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ethybenztropine, also known as Ponalid, is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.

Chemical Structure

Ethybenztropine
Ethybenztropine
CAS#524-83-4 (free base)

Theoretical Analysis

MedKoo Cat#: 525258

Name: Ethybenztropine

CAS#: 524-83-4 (free base)

Chemical Formula: C22H27NO

Exact Mass: 321.2093

Molecular Weight: 321.46

Elemental Analysis: C, 82.20; H, 8.47; N, 4.36; O, 4.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
24815-25-6 (HBr) 524-83-4 (free base) 26598-44-7 (HCl)
Synonym
Ethybenztropine; Ethylbenatropine; Ethylbenztropine; Etibenzatropina; Etibenzatropina [DCIT]; Etybenzatropine; Panolid.
IUPAC/Chemical Name
3alpha-(Diphenylmethoxy)-8-ethyl-1alphaH,5alphaH-nortropane
InChi Key
PHTMLLGDZBZXMW-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H27NO/c1-2-23-19-13-14-20(23)16-21(15-19)24-22(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19-22H,2,13-16H2,1H3
SMILES Code
CCN1C2CC(OC(C3=CC=CC=C3)C4=CC=CC=C4)CC1CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 321.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zakrzewska F. [Direct M motor response in calf muscles during post-tetanic potentiation (PTP) of monosynaptic H reflex before and following administration of ethybenztropine in drug-induced muscle rigidity]. Neurol Neurochir Pol. 1974 Sep-Oct;8(5):719-28. Polish. PubMed PMID: 4427709. 2: Rozear M, Bircher RP, Chai CY, Wang SC. Effects of intracerebroventricular l-hyoscyamine, ethybenztropine and procaine on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside. Int J Neuropharmacol. 1968 Jan;7(1):1-6. PubMed PMID: 5639304.