MedKoo Cat#: 525085 | Name: FR 62765

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FR 62765 is a derivative of WF-3681,a novel aldose reductase inhibitor. It might be a useful drug for diabetic neuropathy.

Chemical Structure

FR 62765
FR 62765
CAS#105346-34-7

Theoretical Analysis

MedKoo Cat#: 525085

Name: FR 62765

CAS#: 105346-34-7

Chemical Formula: C16H18O5

Exact Mass: 290.1154

Molecular Weight: 290.31

Elemental Analysis: C, 66.19; H, 6.25; O, 27.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
FR 62765; FR-62765; FR62765.
IUPAC/Chemical Name
2-Furanpropanoic acid, 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-, ethyl ester
InChi Key
ODHJHYPKZNTPCS-GFCCVEGCSA-N
InChi Code
InChI=1S/C16H18O5/c1-3-20-13(17)10-9-12-14(11-7-5-4-6-8-11)15(19-2)16(18)21-12/h4-8,12H,3,9-10H2,1-2H3/t12-/m1/s1
SMILES Code
O1[C@@H](C(=C(C1=O)OC)c1ccccc1)CCC(=O)OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 290.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nishikawa M, Yoshida K, Okamoto M, Itoh Y, Kohsaka M. Studies on WF-3681, a novel aldose reductase inhibitor. IV. Effect of FR-62765, a derivative of WF-3681, on the diabetic neuropathy in rats. J Antibiot (Tokyo). 1991 Apr;44(4):441-4. PubMed PMID: 1903376.