Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. Moxidectin is a semisynthetic derivative of nemadectin which is produced by fermentation by Streptomyces cyano-griseus. This Streptomyces species was discovered in a soil sample from Australia in the late 1980s collected by an agronomist working for the American Cyanamid company.
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He, Yongwai; Wen, Jing; Zhang, Honglan. Method for preparing Moxidectin. Assignee Peking University Founder Group Co., Ltd., Peop. Rep. China; Chongqing Daxin Pharmaceutical Co., Ltd., PKU International Healthcare Group; PKU International Hospital Group Co., Ltd. CN 104277050. (2015).
Dai, Yao; Du, Zhibo; Wang, Rongliang. Preparation of Moxidectin. Assignee Dalian Jiuxin Biological Chemical Science and Technology Co., Ltd., Peop. Rep. China. CN 104017001. (2014).
Massara, Pasquale; Miraglia, Guiseppe; Caraco, Marco; Sapienza, Stefania; Patel, Jignesh. Improved oxidation process with enhanced safety and use thereof. Assignee Wyeth, John, and Brother Ltd., USA. AU 2006100660. (2006).
