Navuridine, also known as 3’-Azido-2’,3’-dideoxyuridine, is a dideoxyuridine inhibitor of HIV reverse transcriptase that is related to zidovudine. Navuridine exhibits a relatively short half-life and incomplete oral bioavailability and has not been developed into a clinical drug.
MedKoo Cat#: 525733
Name: Navuridine
CAS#: 84472-85-5
Chemical Formula: C9H11N5O4
Exact Mass: 253.0811
Molecular Weight: 253.22
Elemental Analysis: C, 42.69; H, 4.38; N, 27.66; O, 25.27
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 2.0 | 7.90 | |
| DMSO | 126.0 | 497.59 | |
| PBS (pH 7.2) | 1.0 | 3.95 |
The following data is based on the product molecular weight 253.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
