Nanterinone mesylate | CAS#102791-74-2 | Vasodilating Drug

MedKoo Cat#: 525728 | Name: Nanterinone mesylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nanterinone mesylate is a novel positive inotropic and balanced-type vasodilating drug, only partially based on phosphodiesterase III inhibition. Nanterinone exhibits acute hemodynamic effects in patients with mild to moderate heart failure.

Chemical Structure

Nanterinone mesylate

CAS#102791-74-2

Theoretical Analysis

MedKoo Cat#: 525728

Name: Nanterinone mesylate

CAS#: 102791-74-2

Chemical Formula: C16H19N3O4S

Exact Mass: 349.1096

Molecular Weight: 349.41

Elemental Analysis: C, 55.00; H, 5.48; N, 12.03; O, 18.32; S, 9.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

UK 61260; UK-61260; UK61260; Nanterinone mesylate

IUPAC/Chemical Name

6-(2,4-dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one methanesulfonate

InChi Key

OZIIHULZOTWACX-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H15N3O.CH4O3S/c1-9-6-13(18-8-10(2)16-11(18)3)7-12-4-5-14(19)17-15(9)12;1-5(2,3)4/h4-8H,1-3H3,(H,17,19);1H3,(H,2,3,4)

SMILES Code

O=C1NC2=C(C=C(N3C=C(C)N=C3C)C=C2C)C=C1.CS(=O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 349.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Remme WJ, van der Ent M, Bartels GL, van Schelven D, van Hoogenhuyze DC, Krauss XH, Kruijssen HA, Storm CJ. Acute hemodynamic effects and preload-dependent cardiovascular profile of the partial phosphodiesterase inhibitor nanterinone in patients with mild to moderate heart failure. Cardiovasc Drugs Ther. 1996 May;10(2):137-44. PubMed PMID: 8842505.