CS 722 | CAS#144886-17-9 | Muscle Relaxant

MedKoo Cat#: 524901 | Name: CS 722

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CS 722 is a centrally acting muscle relaxant. CS-722 exerts its muscle relaxant action by affecting both the supraspinal structure and the spinal cord.

Chemical Structure

CS 722

CAS#144886-17-9

Theoretical Analysis

MedKoo Cat#: 524901

Name: CS 722

CAS#: 144886-17-9

Chemical Formula: C16H20Cl2N2O4

Exact Mass: 374.0800

Molecular Weight: 375.25

Elemental Analysis: C, 51.21; H, 5.37; Cl, 18.90; N, 7.47; O, 17.05

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

CS 722; CS-722; CS722.

IUPAC/Chemical Name

4-Chloro-2-(2-hydroxy-3-morpholinopropyl)-5-phenyl-4-isoxazolin-3-on

InChi Key

KIWUOCZHZROUNT-BTQNPOSSSA-N

InChi Code

InChI=1S/C16H19ClN2O4.ClH/c17-14-15(12-4-2-1-3-5-12)23-19(16(14)21)11-13(20)10-18-6-8-22-9-7-18;/h1-5,13,20H,6-11H2;1H/t13-;/m1./s1

SMILES Code

o1n(c(c(c1c1ccccc1)Cl)=O)C[C@@H](CN1CCOCC1)O.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 375.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tanabe M, Kaneko T. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313(3):187-9. PubMed PMID: 8911914. 2: Marszalec W, Song JH, Narahashi T. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119(1):126-32. PubMed PMID: 8872365; PubMed Central PMCID: PMC1915728. 3: Tanabe M, Ishizuka H, Murayama T, Kaneko T, Tonohiro T, Sakai J, Nagano M, Sasahara K, Iwata N. Sites of action of CS-722, a newly synthesized centrally acting muscle relaxant. Jpn J Pharmacol. 1993 Nov;63(3):385-9. PubMed PMID: 8107330. 4: Tanabe M, Kaneko T, Tonohiro T, Iwata N. The pharmacological properties of CS-722, a newly synthesized centrally acting muscle relaxant. Neuropharmacology. 1992 Oct;31(10):1059-66. PubMed PMID: 1436388. 5: Tanabe M, Kaneko T, Tonohiro T, Iwata N. Mechanisms of spinal reflex depressant effects of CS-722, a newly synthesized centrally acting muscle relaxant, in spinal rats. Neuropharmacology. 1992 Sep;31(9):949-54. PubMed PMID: 1436401.