MedKoo Cat#: 524865 | Name: CP-671906

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-671906 is a neuropeptide Y1 receptor antagonists. It increases blood pressure and food intake in rat models. These data suggest a potential role for Y1R in the regulation of food intake in rodents.

Chemical Structure

CP-671906
CP-671906
CAS#332178-44-6

Theoretical Analysis

MedKoo Cat#: 524865

Name: CP-671906

CAS#: 332178-44-6

Chemical Formula: C22H27Cl2N5O2

Exact Mass: 463.1542

Molecular Weight: 464.39

Elemental Analysis: C, 56.90; H, 5.86; Cl, 15.27; N, 15.08; O, 6.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
CP-671906; CP 671906; CP671906; UNII-GLZ1WA47Q8; CP-671906-01.
IUPAC/Chemical Name
1,2-Ethanediamine, N-(3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo(1,5-a)pyrimidin-7-yl)-N'-(tetrahydro-2H-pyran-4-yl)-
InChi Key
CVABPTLRAQIZJU-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H27Cl2N5O2/c1-13-10-19(26-7-6-25-15-4-8-31-9-5-15)29-22(27-13)20(14(2)28-29)21-17(23)11-16(30-3)12-18(21)24/h10-12,15,25-26H,4-9H2,1-3H3
SMILES Code
Cc1cc(n2c(n1)c(c(n2)C)c3c(cc(cc3Cl)OC)Cl)NCCNC4CCOCC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 464.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Griffith DA, Hargrove DM, Maurer TS, Blum CA, De Lombaert S, Inthavongsay JK, Klade LE, Mack CM, Rose CR, Sanders MJ, Carpino PA. Discovery and evaluation of pyrazolo[1,5-a]pyrimidines as neuropeptide Y1 receptor antagonists. Bioorg Med Chem Lett. 2011 May 1;21(9):2641-5. doi: 10.1016/j.bmcl.2010.12.116. Epub 2011 Jan 7. PubMed PMID: 21295475.