CP-664511 | CAS#379692-00-9 | Alpha4bet1/VCAM-1 Inhibitor

MedKoo Cat#: 524863 | Name: CP-664511

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-664511 is a potent compound that is a alpha4beta1/vascular cell adhesion molecule-1 (VCAM-1) inhibitor which has therapeutic potential in treating allergic airway disease.

Chemical Structure

CP-664511

CAS#379692-00-9

Theoretical Analysis

MedKoo Cat#: 524863

Name: CP-664511

CAS#: 379692-00-9

Chemical Formula: C28H34N4O6

Exact Mass: 522.2478

Molecular Weight: 522.59

Elemental Analysis: C, 64.35; H, 6.56; N, 10.72; O, 18.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CP-664511; CP 664511; CP664511; UNII-W1AEF8025F.

IUPAC/Chemical Name

5-Isoxazolepropanoic acid, 3-((1S)-1-(((3-methoxy-4-((((2-methylphenyl)amino)carbonyl)amino)phenyl)acetyl)amino)-3-methylbutyl)-

InChi Key

USEDUTJSKDZBGX-QHCPKHFHSA-N

InChi Code

InChI=1S/C28H34N4O6/c1-17(2)13-23(24-16-20(38-32-24)10-12-27(34)35)29-26(33)15-19-9-11-22(25(14-19)37-4)31-28(36)30-21-8-6-5-7-18(21)3/h5-9,11,14,16-17,23H,10,12-13,15H2,1-4H3,(H,29,33)(H,34,35)(H2,30,31,36)/t23-/m0/s1

SMILES Code

Cc1ccccc1NC(=O)Nc2ccc(cc2OC)CC(=O)N[C@@H](CC(C)C)c3cc(on3)CCC(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 522.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kudlacz E, Whitney C, Andresen C, Duplantier A, Beckius G, Chupak L, Klein A, Kraus K, Milici A. Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule alpha4beta1 antagonists. J Pharmacol Exp Ther. 2002 May;301(2):747-52. PubMed PMID: 11961081.