CP-601932 | CAS#357425-68-4 | nAChR Partial Agonist

MedKoo Cat#: 524856 | Name: CP-601932 (free base)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-601932 (free base) is a selective α(4) β(2) nicotinic acetylcholine receptors partial agonist.

Chemical Structure

CP-601932 (free base)

CAS#357425-68-4

Theoretical Analysis

MedKoo Cat#: 524856

Name: CP-601932 (free base)

CAS#: 357425-68-4

Chemical Formula: C12H12F3N

Exact Mass: 227.0922

Molecular Weight: 227.23

Elemental Analysis: C, 63.43; H, 5.32; F, 25.08; N, 6.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CP-601932; CP 601932; CP601932; CP-601,927; UNII-VI5LR1EU47.

IUPAC/Chemical Name

1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-(trifluoromethyl)-, (1R,5S)-

InChi Key

RNOBTWYQAWEZHH-JGVFFNPUSA-N

InChi Code

InChI=1S/C12H12F3N/c13-12(14,15)9-1-2-10-7-3-8(6-16-5-7)11(10)4-9/h1-2,4,7-8,16H,3,5-6H2/t7-,8+/m0/s1

SMILES Code

c1cc2c(cc1C(F)(F)F)[C@@H]3C[C@H]2CNC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 227.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Weber ML, Hofland CM, Shaffer CL, Flik G, Cremers T, Hurst RS, Rollema H. Therapeutic doses of antidepressants are projected not to inhibit human α4β2 nicotinic acetylcholine receptors. Neuropharmacology. 2013 Sep;72:88-95. doi: 10.1016/j.neuropharm.2013.04.027. Epub 2013 Apr 30. PubMed PMID: 23639435. 2: Campion SN, Hurtt ME, Chatman LA, Cappon GD. Toxicity study in juvenile rats with the α4β2 nicotinic acetylcholine receptor partial agonist CP-601,927. Birth Defects Res B Dev Reprod Toxicol. 2011 Aug;92(4):323-32. doi: 10.1002/bdrb.20298. Epub 2011 May 18. PubMed PMID: 21594972.