Anguizole is a potent NS4B-AH2 inhibitor. Anguizole disrupts all of NS4B-AH2-mediated biological functions of NS4B. hronic hepatitis C virus (HCV) infection is responsible for severe liver diseases including liver cirrhosis and hepatocellular carcinoma. An HCV non-structural protein 4B (NS4B) plays an essential role in viral RNA genome replication by building multi-vesicular structures around endoplasmic reticulum membranes.
MedKoo Cat#: 326706
Name: Anguizole
CAS#: 442666-98-0
Chemical Formula: C17H11ClF2N4O2S
Exact Mass: 408.0259
Molecular Weight: 408.81
Elemental Analysis: C, 49.95; H, 2.71; Cl, 8.67; F, 9.29; N, 13.71; O, 7.83; S, 7.84
The following data is based on the product molecular weight 408.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
