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MedKoo Cat#: 524838 | Name: CP-409092

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-409092 is a GABA(A) partial agonist developed for the treatment of anxiety.

Chemical Structure

CP-409092
CP-409092
CAS#194098-25-4

Theoretical Analysis

MedKoo Cat#: 524838

Name: CP-409092

CAS#: 194098-25-4

Chemical Formula: C17H19N3O2

Exact Mass: 297.1477

Molecular Weight: 297.35

Elemental Analysis: C, 68.67; H, 6.44; N, 14.13; O, 10.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CP-409092; CP409092; CP 409092; UNII-420WLS764W.
IUPAC/Chemical Name
1H-Indole-3-carboxamide, 4,5,6,7-tetrahydro-N-(4-((methylamino)methyl)phenyl)-4-oxo-
InChi Key
XFJIYNUISLDNLP-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H19N3O2/c1-18-9-11-5-7-12(8-6-11)20-17(22)13-10-19-14-3-2-4-15(21)16(13)14/h5-8,10,18-19H,2-4,9H2,1H3,(H,20,22)
SMILES Code
CNCc1ccc(NC(=O)c2c[nH]c3CCCC(=O)c23)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 297.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kamel A, Colizza K, Gunduz M, Harriman S, Obach RS. In vitro-in vivo correlation for intrinsic clearance for CP-409,092 and sumatriptan: a case study to predict the in vivo clearance for compounds metabolized by monoamine oxidase. Xenobiotica. 2012 Apr;42(4):355-62. doi: 10.3109/00498254.2011.630490. Epub 2011 Nov 22. PubMed PMID: 22106962. 2: Sawant AD, Miller EL, Duignan DB, Brodfuehrer J, Winter SM, Nelson FR, Kamel A, Obach RS, Vaz AD. Understanding the clinical pharmacokinetics of a GABAA partial agonist by application of in vitro tools. Xenobiotica. 2010 Jul;40(7):476-84. doi: 10.3109/00498254.2010.481057. PubMed PMID: 20429841. 3: Kamel A, Obach RS, Tseng E, Sawant A. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist [(14)C]CP-409,092 in rats. Xenobiotica. 2010 Jun;40(6):400-14. doi: 10.3109/00498251003710269. PubMed PMID: 20334492. 4: Sutton SC, Evans LA, Fortner JH, McCarthy JM, Sweeney K. Dog colonoscopy model for predicting human colon absorption. Pharm Res. 2006 Jul;23(7):1554-63. Epub 2006 Jun 21. PubMed PMID: 16783662.