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MedKoo Cat#: 524816 | Name: CP 74667

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP 74667 is a new fluoroquinolone that has good activity against several gram-positive and gram-negative pathogens.

Chemical Structure

CP 74667
CP 74667
CAS#108461-05-8

Theoretical Analysis

MedKoo Cat#: 524816

Name: CP 74667

CAS#: 108461-05-8

Chemical Formula: C20H22FN3O3

Exact Mass: 371.1645

Molecular Weight: 371.41

Elemental Analysis: C, 64.68; H, 5.97; F, 5.12; N, 11.31; O, 12.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CP 74667; CP74667; CP-74667; UNII-D66A707X1B.
IUPAC/Chemical Name
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo(3.2.1)oct-3-yl)-4-oxo-
InChi Key
ALRZZABRVIYCNY-BETUJISGSA-N
InChi Code
InChI=1S/C20H22FN3O3/c1-22-12-4-5-13(22)9-23(8-12)18-7-17-14(6-16(18)21)19(25)15(20(26)27)10-24(17)11-2-3-11/h6-7,10-13H,2-5,8-9H2,1H3,(H,26,27)/t12-,13+
SMILES Code
CN1[C@H]2CC[C@@H]1CN(C2)c3cc4N(C=C(C(=O)O)C(=O)c4cc3F)C5CC5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 371.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gu JW, Fang W, Chin NX, Neu HC. In vitro activity of CP-74,667. A new fluoroquinolone compared with other quinolones. Diagn Microbiol Infect Dis. 1992 Sep-Oct;15(7):613-20. PubMed PMID: 1330421. 2: Jones RN, Erwin ME. In vitro activity of CP-74667 compared with four other fluoroquinolones. Diagn Microbiol Infect Dis. 1992 Aug;15(6):531-6. PubMed PMID: 1330419. 3: Girard D, Gootz TD, McGuirk PR. Pharmacokinetic studies of CP-74,667, a new quinolone, in laboratory animals. Antimicrob Agents Chemother. 1992 Aug;36(8):1671-6. PubMed PMID: 1329625; PubMed Central PMCID: PMC192028.