MedKoo Cat#: 526588 | Name: Zometapine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Zometapine is an antidepressant drug which is a pyrazolodiazepine derivative. Its molecular structure closely resembles benzodiazepines and is unrelated to other antidepressant drug classes.

Chemical Structure

Zometapine
Zometapine
CAS#51022-73-2

Theoretical Analysis

MedKoo Cat#: 526588

Name: Zometapine

CAS#: 51022-73-2

Chemical Formula: C15H15FN4O

Exact Mass: 286.1230

Molecular Weight: 286.31

Elemental Analysis: C, 62.93; H, 5.28; F, 6.64; N, 19.57; O, 5.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CI 716; CI-716; CI716; Zometapine; Zolazepamum; Flupyrazapon
IUPAC/Chemical Name
4-(2-fluorophenyl)-1,3,8-trimethyl-6,8-dihydropyrazolo[3,4-e][1,4]diazepin-7(1H)-one
InChi Key
GDSCFOSHSOWNDL-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H15FN4O/c1-9-13-14(10-6-4-5-7-11(10)16)17-8-12(21)19(2)15(13)20(3)18-9/h4-7H,8H2,1-3H3
SMILES Code
O=C1CN=C(C2=CC=CC=C2F)C3=C(N(C)N=C3C)N1C
Appearance
White to off-white solid powder.
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 286.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Katz RJ. Effects of zometapine, a structurally novel antidepressant, in an animal model of depression. Pharmacol Biochem Behav. 1984 Oct;21(4):487-90. PubMed PMID: 6542226. 2: Fairchild CJ, Rush AJ, Vasavada N, Giles DE, Khatami M. Which depressions respond to placebo? Psychiatry Res. 1986 Jul;18(3):217-26. PubMed PMID: 3529150.