CP 65207 | CAS#96865-21-3 | Broad-spectrum Antimicrobial Agent

MedKoo Cat#: 524809 | Name: CP 65207

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP 65,207 is a new broad-spectrum penem antimicrobial agent that is a 1:1 mixture of two stereoisomers.

Chemical Structure

CP 65207

CAS#96865-21-3

Theoretical Analysis

MedKoo Cat#: 524809

Name: CP 65207

CAS#: 96865-21-3

Chemical Formula: C12H14NNaO5S3

Exact Mass:

Molecular Weight: 371.43

Elemental Analysis: C, 38.80; H, 3.80; N, 3.77; Na, 6.19; O, 21.54; S, 25.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

CP 65207; CP-65207 ; CP65207;CP 81054.

IUPAC/Chemical Name

4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-((tetrahydro-3-thienyl)thio)-, S-oxide, monosodium salt, (5R-(5alpha,6alpha(R*)))-

InChi Key

MRHMJKHFABHUKB-VASRXWSJSA-M

InChi Code

InChI=1S/C12H15NO5S3.Na/c1-5(14)7-9(15)13-8(11(16)17)12(20-10(7)13)19-6-2-3-21(18)4-6;/h5-7,10,14H,2-4H2,1H3,(H,16,17);/q;+1/p-1/t5-,6?,7+,10-,21?;/m1./s1

SMILES Code

C[C@H]([C@@H]1[C@@H]2N(C1=O)C(=C(S2)SC3CCS(=O)C3)C(=O)[O-])O.[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 371.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Foulds G, Knirsch AK, Lazar JD, Tensfelt TG, Gerber N. Pharmacokinetics of the penem CP-65,207 and its separate stereoisomers in humans. Antimicrob Agents Chemother. 1991 Apr;35(4):665-71. Erratum in: Antimicrob Agents Chemother 1991 Aug;35(8):1695. PubMed PMID: 2069372; PubMed Central PMCID: PMC245076. 2: Gootz T, Girard D, Schelkley W, Tensfeldt T, Foulds G, Kellogg M, Stam J, Campbell B, Jasys J, Kelbaugh P, et al. Pharmacokinetic studies in animals of a new parenteral penem CP-65,207 and its oral prodrug ester. J Antibiot (Tokyo). 1990 Apr;43(4):422-32. PubMed PMID: 2351614. 3: Gootz T, Retsema J, Girard A, Hamanaka E, Anderson M, Sokolowski S. In vitro activity of CP-65,207, a new penem antimicrobial agent, in comparison with those of other agents. Antimicrob Agents Chemother. 1989 Aug;33(8):1160-6. PubMed PMID: 2679370; PubMed Central PMCID: PMC172617.