WAY 150138 | CAS#273388-09-3 | Herpes Simplex Virus Inhibitor

MedKoo Cat#: 526572 | Name: WAY 150138

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WAY 150138 can cause the inhibition of the herpes simplex virus.

Chemical Structure

WAY 150138

CAS#273388-09-3

Theoretical Analysis

MedKoo Cat#: 526572

Name: WAY 150138

CAS#: 273388-09-3

Chemical Formula: C22H18Cl2FN3O3S

Exact Mass: 493.0430

Molecular Weight: 494.36

Elemental Analysis: C, 53.45; H, 3.67; Cl, 14.34; F, 3.84; N, 8.50; O, 9.71; S, 6.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

WAY 150138; WAY150138; WAY-150138

IUPAC/Chemical Name

N-(3-chloro-4-(3-(5-chloro-2,4-dimethoxyphenyl)thioureido)phenyl)-2-fluorobenzamide

InChi Key

NPZHFWHOVNAVCF-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H18Cl2FN3O3S/c1-30-19-11-20(31-2)18(10-15(19)24)28-22(32)27-17-8-7-12(9-14(17)23)26-21(29)13-5-3-4-6-16(13)25/h3-11H,1-2H3,(H,26,29)(H2,27,28,32)

SMILES Code

O=C(NC1=CC=C(NC(NC2=CC(Cl)=C(OC)C=C2OC)=S)C(Cl)=C1)C3=CC=CC=C3F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 494.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Newcomb WW, Brown JC. Inhibition of herpes simplex virus replication by WAY-150138: assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation. J Virol. 2002 Oct;76(19):10084-8. PubMed PMID: 12208991; PubMed Central PMCID: PMC136520. 2: Newcomb WW, Thomsen DR, Homa FL, Brown JC. Assembly of the herpes simplex virus capsid: identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids. J Virol. 2003 Sep;77(18):9862-71. PubMed PMID: 12941896; PubMed Central PMCID: PMC224603. 3: Pesola JM, Zhu J, Knipe DM, Coen DM. Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production. J Virol. 2005 Dec;79(23):14516-25. Erratum in: J Virol. 2006 Jun;80(12):6196. PubMed PMID: 16282451; PubMed Central PMCID: PMC1287588.