MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 526563 | Name: Way 100289

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Way 100289 is a selective 5-HT3 receptor antagonist.

Chemical Structure

Way 100289
Way 100289
CAS#136013-69-9

Theoretical Analysis

MedKoo Cat#: 526563

Name: Way 100289

CAS#: 136013-69-9

Chemical Formula: C20H27N3O3

Exact Mass: 357.2052

Molecular Weight: 357.45

Elemental Analysis: C, 67.20; H, 7.61; N, 11.76; O, 13.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Way 100289; Way-100289; Way100289
IUPAC/Chemical Name
2-(cyclopropylmethoxy)-N-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)carbamoyl)benzamide
InChi Key
VFRIHPWRNNTKEX-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H27N3O3/c1-23-15-8-9-16(23)11-14(10-15)21-20(25)22-19(24)17-4-2-3-5-18(17)26-12-13-6-7-13/h2-5,13-16H,6-12H2,1H3,(H2,21,22,24,25)
SMILES Code
O=C(NC(NC1CC(N2C)CCC2C1)=O)C3=CC=CC=C3OCC4CC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 357.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rodgers RJ, Cole JC, Tredwell JM. Profile of action of 5-HT3 receptor antagonists, ondansetron and WAY 100289, in the elevated plus-maze test of anxiety of mice. Psychopharmacology (Berl). 1995 Feb;117(3):306-12. PubMed PMID: 7770606. 2: Hodges H, Sowinski P, Sinden JD, Netto CA, Fletcher A. The selective 5-HT3 receptor antagonist, WAY100289, enhances spatial memory in rats with ibotenate lesions of the forebrain cholinergic projection system. Psychopharmacology (Berl). 1995 Feb;117(3):318-32. PubMed PMID: 7770608. 3: Bill DJ, Fletcher A, Glenn BD, Knight M. Behavioural studies on WAY100289, a novel 5-HT3 receptor antagonist, in two animal models of anxiety. Eur J Pharmacol. 1992 Aug 6;218(2-3):327-34. PubMed PMID: 1358637.