MedKoo Cat#: 526503 | Name: Triclofenol piperazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Triclofenol piperazine helps with the treatment of patients imfected with parasite such as hookworms.

Chemical Structure

Triclofenol piperazine
Triclofenol piperazine
CAS#5714-82-9

Theoretical Analysis

MedKoo Cat#: 526503

Name: Triclofenol piperazine

CAS#: 5714-82-9

Chemical Formula: C10H11Cl3N2O2

Exact Mass: 295.9886

Molecular Weight: 297.56

Elemental Analysis: C, 40.36; H, 3.73; Cl, 35.74; N, 9.41; O, 10.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
CI-416; CI416; CI 416; Triclofenol piperazine; Triclofenol piperazate; Triclofenol piperazina
IUPAC/Chemical Name
piperazin-2-one compound with 2,4,5-trichlorophenol (1:1)
InChi Key
QGQSHAPJZVFLPH-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H3Cl3O.C4H8N2O/c7-3-1-5(9)6(10)2-4(3)8;7-4-3-5-1-2-6-4/h1-2,10H;5H,1-3H2,(H,6,7)
SMILES Code
OC1=CC(Cl)=C(Cl)C=C1Cl.O=C2NCCNC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 297.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: SHORT FW, ELSLAGER EF. INTESTINAL ANTHELMINTICS. I. THE PREPARATION OF BIS(2,4,5TRICHLOROPHENOL)-PIPERAZINE SALT (TRICLOFENOL PIPERAZINE) AND OTHER PHENOL-PIPERAZINE SALTS. J Med Pharm Chem. 1962 May;91:642-6. PubMed PMID: 14056397. 2: WAGNER ED, ANDERSON MG Jr. TREATMENT OF INTESTINAL HELMINTHS IN NIGERIA WITH TRICLOFENOL PIPERAZINE. Trans R Soc Trop Med Hyg. 1963 Jul;57:293-6. PubMed PMID: 14047027. 3: PENA CHAVARRIA A, LIZANO C, COURTNEY KO, THOMPSON PE. THE EFFECTS OF TRICLOFENOL PIPERAZINE IN PATIENTS PARASITIZED BY HOOKWORMS, ASCARDIDS, OR TRICHURIDS. Am J Trop Med Hyg. 1963 May;12:378-82. PubMed PMID: 14044748. 4: WAKS J. The hookworm problem in the greater Buenos Aires area with particular references to the therapeutic efficacy of triclofenol piperazine. Am J Trop Med Hyg. 1963 Jan;12:56-9. PubMed PMID: 13998398. 5: Hunter GW 3rd, Davidson C. The effectiveness of a single dose of triclofenol piperazine (Ranestol) against light hookworm infections. Mil Med. 1966 Jan;131(1):48-51. PubMed PMID: 4954872.