CK 2289 | CAS# 101183-99-7

MedKoo Cat#: 524744 | Name: CK 2289

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CK 2289 is an inhibitor of type III cyclic 3'5'-adenosine monophosphate phosphodiesterase with potential utility in the treatment of congestive heart failure.

Chemical Structure

CK 2289

CAS# 101183-99-7

Theoretical Analysis

MedKoo Cat#: 524744

Name: CK 2289

CAS#: 101183-99-7

Chemical Formula: C15H14N4O2

Exact Mass: 282.1117

Molecular Weight: 282.30

Elemental Analysis: C, 63.82; H, 5.00; N, 19.85; O, 11.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

CK 2289; CK-2289; CK2289.

IUPAC/Chemical Name

2H-Imidazol-2-one, 4-ethyl-1,3-dihydro-5-(4-(1H-imidazol-1-yl)benzoyl)-

InChi Key

VQVLBYWJKODQIR-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H14N4O2/c1-2-12-13(18-15(21)17-12)14(20)10-3-5-11(6-4-10)19-8-7-16-9-19/h3-9,17-18H,2H2,1H3

SMILES Code

c1cncn1c1ccc(C(c2c([nH]c([nH]2)=O)CC)=O)cc1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 282.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chen W, Hu XY, Lu HN. [Impacts of Biochar Input on Mineralization of Native Soil Organic Carbon]. Huan Jing Ke Xue. 2015 Jun;36(6):2300-5. Chinese. PubMed PMID: 26387339. 2: Avesani CM, Draibe SA, Kamimura MA, Cendoroglo M, Pedrosa A, Castro ML, Cuppari L. Assessment of body composition by dual energy X-ray absorptiometry, skinfold thickness and creatinine kinetics in chronic kidney disease patients. Nephrol Dial Transplant. 2004 Sep;19(9):2289-95. Epub 2004 Jul 13. PubMed PMID: 15252158. 3: Greenberg SS, Paul J, Luisi A. Pharmacological comparison of CK-2289, an inodilator agent, with milrinone and enoximone. Arch Int Pharmacodyn Ther. 1991 Jan-Feb;309:103-24. PubMed PMID: 1653560.