CI-925 is an Angiotensin Converting Enzyme Inhibitor, with antihypertensive activity. As a prodrug, CI-925 is hydrolyzed which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex.
MedKoo Cat#: 524731
Name: CI-925
CAS#: 109715-88-0
Chemical Formula: C27H34N2O7
Exact Mass: 498.2366
Molecular Weight: 498.57
Elemental Analysis: C, 65.04; H, 6.87; N, 5.62; O, 22.46
The following data is based on the product molecular weight 498.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
