MedKoo Cat#: 524627 | Name: Cgp 33304

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cgp 33304 is a dual leukotriene receptor antagonists and phospholipase A2 inhibiting agent. It may prevent hypoxia secondary to leukotriene induced bronchoconstriction in shock states. CGP 33304 has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock.

Chemical Structure

Cgp 33304
Cgp 33304
CAS#111130-14-4

Theoretical Analysis

MedKoo Cat#: 524627

Name: Cgp 33304

CAS#: 111130-14-4

Chemical Formula: C23H25BrN5NaO5

Exact Mass: 553.0937

Molecular Weight: 554.37

Elemental Analysis: C, 49.83; H, 4.55; Br, 14.41; N, 12.63; Na, 4.15; O, 14.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cgp 33304; Cgp33304; Cgp-33304.
IUPAC/Chemical Name
sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-bromo-2-methylphenyl)carbamoyl)tetrazol-1-ide
InChi Key
RODQJMRHNNVXAG-UHFFFAOYSA-M
InChi Code
InChI=1S/C23H26BrN5O5.Na/c1-4-6-16-19(8-7-15(14(3)30)21(16)31)33-9-5-10-34-20-12-18(13(2)11-17(20)24)25-23(32)22-26-28-29-27-22;/h7-8,11-12H,4-6,9-10H2,1-3H3,(H3,25,26,27,28,29,30,31,32);/q;+1/p-1
SMILES Code
CCCc1c(ccc(c1O)C(=O)C)OCCCOc2cc(c(cc2Br)C)NC(=O)c3[n-]nnn3.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 554.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Levitt MA, Lefer AM. Efficacy of two leukotriene antagonists in rat traumatic shock. Methods Find Exp Clin Pharmacol. 1987 May;9(5):269-73. PubMed PMID: 3613754.