MedKoo Cat#: 524625 | Name: Cgp 31358

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CGP 31358 is a new chemical entity with a novel mechanism of action at the NMDA receptor, and as such may form a tool for understanding the molecular pharmacology of this receptor-channel complex. It binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain.

Chemical Structure

Cgp 31358
Cgp 31358
CAS#125652-47-3

Theoretical Analysis

MedKoo Cat#: 524625

Name: Cgp 31358

CAS#: 125652-47-3

Chemical Formula: C19H19ClN4O2

Exact Mass: 370.1197

Molecular Weight: 370.83

Elemental Analysis: C, 61.54; H, 5.16; Cl, 9.56; N, 15.11; O, 8.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Cgp 31358; Cgp-31358; Cgp31358.
IUPAC/Chemical Name
1H-1,2,4-Triazole-3-carboxamide, 1-(4-(1-(4-chlorophenyl)-1-methylethyl)-2-methoxyphenyl)-
InChi Key
STTFFDLZKCMBQO-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H19ClN4O2/c1-19(2,12-4-7-14(20)8-5-12)13-6-9-15(16(10-13)26-3)24-11-22-18(23-24)17(21)25/h4-11H,1-3H3,(H2,21,25)
SMILES Code
n1(nc(nc1)C(=O)N)c1c(cc(cc1)C(C)(C)c1ccc(cc1)Cl)OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 370.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Baud J, Thedinga K, Portet C, Schmutz M, Bittiger H, Bischoff S, Hauser K, Benedict M, Meier R, Fagg GE. CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain. Neurosci Lett. 1989 Dec 15;107(1-3):184-8. PubMed PMID: 2575726.