MedKoo Cat#: 524568 | Name: CB-403

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CB-403 is a cinnamaldehyde derivative that has antitumor effect through the arrest of cell cycle progression in the G2/M phase. CB403 exerts cytostatic properties by inducing mitotic arrest in cancer cells.

Chemical Structure

CB-403
CB-403
CAS#302356-18-9

Theoretical Analysis

MedKoo Cat#: 524568

Name: CB-403

CAS#: 302356-18-9

Chemical Formula: C17H16O2

Exact Mass: 252.1150

Molecular Weight: 252.31

Elemental Analysis: C, 80.93; H, 6.39; O, 12.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CB-403; CB403; CB 403; UNII-4V9Q0C88UK.
IUPAC/Chemical Name
2-Propenal, 3-(2-((2-methylphenyl)methoxy)phenyl)-
InChi Key
BIYYAALWGHMYTO-UXBLZVDNSA-N
InChi Code
InChI=1S/C17H16O2/c1-14-7-2-3-9-16(14)13-19-17-11-5-4-8-15(17)10-6-12-18/h2-12H,13H2,1H3/b10-6+
SMILES Code
Cc1ccccc1COc2ccccc2/C=C/C=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 252.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jeong HW, Han DC, Son KH, Han MY, Lim JS, Ha JH, Lee CW, Kim HM, Kim HC, Kwon BM. Antitumor effect of the cinnamaldehyde derivative CB403 through the arrest of cell cycle progression in the G2/M phase. Biochem Pharmacol. 2003 Apr 15;65(8):1343-50. PubMed PMID: 12694875.