MedKoo Cat#: 524538 | Name: Brotianide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Brotianide has anti-fasciolidal activity for the treatment of severe infections on animals to remove larvae.

Chemical Structure

Brotianide
Brotianide
CAS#23233-88-7

Theoretical Analysis

MedKoo Cat#: 524538

Name: Brotianide

CAS#: 23233-88-7

Chemical Formula: C15H10Br2ClNO2S

Exact Mass: 460.8488

Molecular Weight: 463.57

Elemental Analysis: C, 38.86; H, 2.17; Br, 34.47; Cl, 7.65; N, 3.02; O, 6.90; S, 6.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Brotianide; Dirian; BAY-VA 4059; BAY-VA-4059; BAY-VA4059.
IUPAC/Chemical Name
2-bromo-6-((4-bromophenyl)carbamothioyl)-4-chlorophenyl acetate
InChi Key
NRFGEDASJHBPPN-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H10Br2ClNO2S/c1-8(20)21-14-12(6-10(18)7-13(14)17)15(22)19-11-4-2-9(16)3-5-11/h2-7H,1H3,(H,19,22)
SMILES Code
c1(C(Nc2ccc(cc2)Br)=S)c(c(Br)cc(c1)Cl)OC(=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 463.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tinar B, Dogan H, Demir S, Akyol CV. Treatment of Dicrocoelium dendriticum with a combination of thiophanate and brotianide. Vet Rec. 1988 Dec 17;123(25):650-1. PubMed PMID: 3218049. 2: Léger N, Notteghem MJ. [The fasciolidal activity of a new compound, brotianide on Echinostoma carponi Richard 1964]. Ann Pharm Fr. 1975 May;33(5):273-7. French. PubMed PMID: 1211790.