BMS-354326 is a highly potent tryptase inhibitor (IC(50)=1.8 nM), which has excellent selectivity against trypsin and most other related serine proteases. The serine protease tryptase has been implicated in allergic and inflammatory diseases and associated with asthma.
MedKoo Cat#: 524469
Name: BMS-354326
CAS#: 708258-16-6
Chemical Formula: C28H40N4O5
Exact Mass: 512.2999
Molecular Weight: 512.64
Elemental Analysis: C, 65.60; H, 7.86; N, 10.93; O, 15.60
The following data is based on the product molecular weight 512.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
