LSN3154567, also known as Nampt-IN-1, is a potent and elective NAMPT inhibitor. Nicotinamide phosphoribosyltransferase (NAMPT) is a promising antitumor target. NAMPT inhibition leads to attenuation of glycolysis, resulting in further perturbation of carbohydrate metabolism in cancer cells.
MedKoo Cat#: 407339
Name: LSN3154567
CAS#: 1698878-14-6
Chemical Formula: C20H25N3O5S
Exact Mass: 419.1515
Molecular Weight: 419.50
Elemental Analysis: C, 57.26; H, 6.01; N, 10.02; O, 19.07; S, 7.64
Solvent | mg/mL | mM | |
---|---|---|---|
Solubility | |||
DMSO | 250.0 | 595.95 |
The following data is based on the product molecular weight 419.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |