Synonym
Amicarbazone; Amicarbazone [ISO]; UNII-7FU145I60E; BAY 314666;
IUPAC/Chemical Name
3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide
InChi Key
GZTFUVZVLYUPRG-IZZDOVSWSA-N
InChi Code
InChI=1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
SMILES Code
CC(C)(C)c1ccc(cc1)/C=C/C(=O)Nc2ccc3c(c2)OCCO3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
337.41
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Dong M, Han W, Ediage EN, Fan L, Tang H, Wang W, Han L, Zhao Z, Song W, Han Z. Dissipation kinetics and degradation mechanism of amicarbazone in soil revealed by a reliable LC-MS/MS method. Environ Sci Pollut Res Int. 2015 Nov;22(22):17518-26. doi: 10.1007/s11356-015-4899-3. Epub 2015 Jul 4. PubMed PMID: 26139399.
2: Dong M, Nie D, Tang H, Rao Q, Qu M, Wang W, Han L, Song W, Han Z. Analysis of amicarbazone and its two metabolites in grains and soybeans by liquid chromatography with tandem mass spectrometry. J Sep Sci. 2015 Jul;38(13):2245-52. doi: 10.1002/jssc.201500265. Epub 2015 May 19. PubMed PMID: 25907799.
3: Yu J, McCullough PE, Grey T. Physiological effects of temperature on turfgrass tolerance to amicarbazone. Pest Manag Sci. 2015 Apr;71(4):571-8. doi: 10.1002/ps.3853. Epub 2014 Aug 13. PubMed PMID: 25045054.
4: Tao Y, Xu J, Liu X, Cheng Y, Liu N, Chen Z, Dong F, Zheng Y. A quick, easy, cheap, effective, rugged, and safe method for the simultaneous detection of four triazolone herbicides in cereals combined with ultrahigh performance liquid chromatography with tandem mass spectrometry. J Sep Sci. 2014 Sep;37(17):2340-8. doi: 10.1002/jssc.201400186. Epub 2014 Jul 15. PubMed PMID: 24923624.
5: Kaur M, Butcher RJ, Jasinski JP, Yathirajan HS, Siddaraju BP. Amicarbazone. Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 28;69(Pt 4):o603. doi: 10.1107/S1600536813007782. Print 2013 Apr 1. PubMed PMID: 23634130; PubMed Central PMCID: PMC3629643.
