MedKoo Cat#: 524171 | Name: AM-1235

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AM-1235 is a drug that acts as a potent and is selective agonist for the cannabinoid receptor CB1.

Chemical Structure

AM-1235
AM-1235
CAS#335161-27-8

Theoretical Analysis

MedKoo Cat#: 524171

Name: AM-1235

CAS#: 335161-27-8

Chemical Formula: C26H26N2O

Exact Mass: 382.2045

Molecular Weight: 382.50

Elemental Analysis: C, 81.64; H, 6.85; N, 7.32; O, 4.18

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Synonym
AM-1235; AM1235; AM 1235;
IUPAC/Chemical Name
(R)-(1-((1-Methylpiperidin-2-yl)methyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
InChi Key
URKVBEKZCMUTQC-HXUWFJFHSA-N
InChi Code
InChI=1S/C26H26N2O/c1-27-16-7-6-11-20(27)17-28-18-24(22-13-4-5-15-25(22)28)26(29)23-14-8-10-19-9-2-3-12-21(19)23/h2-5,8-10,12-15,18,20H,6-7,11,16-17H2,1H3/t20-/m1/s1
SMILES Code
CN1CCCC[C@@H]1Cn2cc(C(=O)c3cccc4ccccc34)c5ccccc25
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 382.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Coronado-Álvarez A, Romero-Cordero K, Macías-Triana L, Tatum-Kuri A, Vera- Barrón A, Budde H, Machado S, Yamamoto T, Imperatori C, Murillo-Rodríguez E. The synthetic CB1 cannabinoid receptor selective agonists: Putative medical uses and their legalization. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Aug 30;110:110301. doi: 10.1016/j.pnpbp.2021.110301. Epub 2021 Mar 17. PMID: 33741446.