BMS-919373 | CAS#1272353-82-8 | Potassium channel Kv1.5 (KCNA5) inhibitor

MedKoo Cat#: 522698 | Name: BMS-919373

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS-919373 is a Potassium channel Kv1.5 (KCNA5) inhibitor for use in atrial fibrillation and acute coronary syndromes. Phase II development is underway in the US and Canada for paroxysmal atrial fibrillation.

Chemical Structure

BMS-919373

CAS#1272353-82-8

Theoretical Analysis

MedKoo Cat#: 522698

Name: BMS-919373

CAS#: 1272353-82-8

Chemical Formula: C25H20N6O2S

Exact Mass: 468.1368

Molecular Weight: 468.54

Elemental Analysis: C, 64.09; H, 4.30; N, 17.94; O, 6.83; S, 6.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BMS-919373; BMS 919373; BMS919373.

IUPAC/Chemical Name

5-(5-phenyl-4-((pyridin-2-ylmethyl)amino)quinazolin-2-yl)pyridine-3-sulfonamide

InChi Key

XGKULQQVQWCASY-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)

SMILES Code

O=S(C1=CC(C2=NC(NCC3=NC=CC=C3)=C4C(C5=CC=CC=C5)=CC=CC4=N2)=CN=C1)(N)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Note: structure was from https://newdrugapprovals.org/2016/04/.

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 468.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.