AMG PERK 44 is a potent and selective PERK inhibitor (IC50 = 6 nM). Exhibits >160-fold selectivity for PERK over B-Raf and GCN2, as well as a panel of 387 other kinases. This drug is orally bioavailable.
MedKoo Cat#: 523129
Name: AMG PERK 44
CAS#: none
Chemical Formula: C34H29ClN4O2
Exact Mass:
Molecular Weight: 561.08
Elemental Analysis: C, 72.78; H, 5.21; Cl, 6.32; N, 9.99; O, 5.70
The following data is based on the product molecular weight 561.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
