LOC14 is a high affinity protein disulfide isomerase (PDI) modulator (Kd = 62 nM). It forces PDI to adopt an oxidized conformation and suppresses its activty. LOC14 is neuroprotective.
MedKoo Cat#: 523127
Name: LOC14
CAS#: 877963-94-5
Chemical Formula: C16H19N3O2S
Exact Mass: 317.1198
Molecular Weight: 317.41
Elemental Analysis: C, 60.55; H, 6.03; N, 13.24; O, 10.08; S, 10.10
The following data is based on the product molecular weight 317.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
