MedKoo Cat#: 318762 | Name: Sulfacytine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfacytine is a short-acting sulfonamide antibiotic, taken orally for treatment against bacterial infections. Sulfonamides, as a group of antibiotics, work by inhibiting the bacterial synthesis of folate.

Chemical Structure

Sulfacytine
Sulfacytine
CAS#17784-12-2

Theoretical Analysis

MedKoo Cat#: 318762

Name: Sulfacytine

CAS#: 17784-12-2

Chemical Formula: C12H14N4O3S

Exact Mass: 294.0787

Molecular Weight: 294.33

Elemental Analysis: C, 48.97; H, 4.79; N, 19.04; O, 16.31; S, 10.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
CI636; CI-636; CI 636; Sulfacytine; Renoquid; Sulfacitinum
IUPAC/Chemical Name
4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzenesulfonamide
InChi Key
SIBQAECNSSQUOD-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17)
SMILES Code
O=C1N(CC)C=CC(NS(=O)(C2=CC=C(N)C=C2)=O)=N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jensen PA, Mueller JM. Sulfacytine vs. sulfisoxazole for urinary tract infections in an obstetric-gynecologic population. Curr Ther Res Clin Exp. 1976 Jun;19(6):573-8. PubMed PMID: 819216. 2: Sulfacytine. Med Lett Drugs Ther. 1976 May 7;18(10):43-4. PubMed PMID: 1272189. 3: Cohen AE. Sulfacytine in uncomplicated urinary tract infections. Double-blind comparison with sulfisoxazole. Urology. 1976 Mar;7(3):267-71. PubMed PMID: 769287. 4: Way KE. Double-blind comparison of sulfacytine, a new sulfonamide, with sulfisoxazole in acute uncomplicated urinary tract infections. Curr Ther Res Clin Exp. 1976 Feb;19(2):220-9. PubMed PMID: 813961. 5: Hughes J, Roberts LC, Coppridge AJ. Sulfacytine: a new sulfonamide. Double-blind comparison with sulfisoxazole in acute uncomplicated urinary tract infections. J Urol. 1975 Dec;114(6):912-4. PubMed PMID: 1195474. 6: Moyer CE, Goulet JR, Smith TC. A study of the effects of long-term administration of sulfacytine, a new sulfonamide, on the kidney function of man. J Clin Pharmacol New Drugs. 1972 Jul;12(7):254-8. PubMed PMID: 4483531. 7: McCarthy CG. Clinical study new short acting sulfanilamide (sulfacytine). Protocol 636-48. Rocky Mt Med J. 1972 May;69(5):45-8. PubMed PMID: 4556218. 8: Berman HA, Barza M, Weinstein L. Serum sulfonamide concentration after oral administration: comparison of results of chemical assay with two bioassay techniques. Antimicrob Agents Chemother. 1972 Mar;1(3):268-73. PubMed PMID: 5045472; PubMed Central PMCID: PMC444204. 9: Moffat NA, Wenzel FJ. The treatment of urinary tract infections with sulfacytine, a new soluble sulfonamide. Curr Ther Res Clin Exp. 1971 May;13(5):286-91. PubMed PMID: 4998391. 10: Heifetz CL, Chodubski JA, DeCarlo MO, Fisher MW. Disc-agar diffusion microbiological assay procedure for determining serum and urine levels of sulfacytine and other sulfonamides. Appl Microbiol. 1971 May;21(5):893-8. PubMed PMID: 4930038; PubMed Central PMCID: PMC377304.