MedKoo Cat#: 318478 | Name: Phenindamine Tartrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenindamine Tartrate is an antihistamine and anticholinergic closely related to cyproheptadine. It was developed by Hoffman-La Roche in the late 1940s. It is used to treat symptoms of the common cold and allergies, such as sneezing, itching, rashes, and hives. Its efficacy against some symptoms of opioid withdrawal was researched in the 1950s and 1960s in a number of countries.

Chemical Structure

Phenindamine Tartrate
Phenindamine Tartrate
CAS# 569-59-5 (tartrate)

Theoretical Analysis

MedKoo Cat#: 318478

Name: Phenindamine Tartrate

CAS#: 569-59-5 (tartrate)

Chemical Formula: C23H25NO6

Exact Mass:

Molecular Weight: 411.45

Elemental Analysis: C, 67.14; H, 6.12; N, 3.40; O, 23.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
82-88-2 (free base); 569-59-5 (tartrate); 5503-08-2 (HCl)
Synonym
Phenindamine Tartrate; Pernovine, Plegine, Phenindamine, Nolahist; Thephorin; Phenindamine tartrate; Mixture Name, PV Tussin Syrup, PV Tussin Tablet, Nolahist (TN), Phenindamine bitartrate; Phenindamine hydrogen tartrate; Phenindamine tartrate (USAN); Phenindamine tartrate [USAN];
IUPAC/Chemical Name
2,3-dihydroxybutanedioic acid;2-methyl-9-phenyl-1,3,4,9-tetrahydroindeno[2,1-c]pyridine
InChi Key
WFXURHIXPXVPGM-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H19N.C4H6O6/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14;5-1(3(7)8)2(6)4(9)10/h2-10,19H,11-13H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)
SMILES Code
CN1CCC2=C(C1)C(C3=CC=CC=C23)C4=CC=CC=C4.C(C(C(=O)O)O)(C(=O)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 411.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tscherne RJ, Umagat H. Determination of isophenindamine in phenindamine tartrate using an argentated high-performance liquid chromatographic mobile phase. J Pharm Sci. 1980 Mar;69(3):342-4. PubMed PMID: 7381716. 2: Witek TJ Jr, Canestrari DA, Miller RD, Yang JY, Riker DK. The effects of phenindamine tartrate on sleepiness and psychomotor performance. J Allergy Clin Immunol. 1992 Dec;90(6 Pt 1):953-61. PubMed PMID: 1360991. 3: UHLE CA, KNOCH HR. Bladder dysfunction following ingestion of phenindamine tartrate (thephorin). J Am Med Assoc. 1951 Aug 4;146(14):1319-20. PubMed PMID: 14850285.