SAR-629 is a MGL inhibitor or 2-AG degradation inhibitor. Monoglyceride lipase (MGL) is a serine hydrolase that hydrolyses 2-arachidonoylglycerol (2-AG) into arachidonic acid and glycerol. 2-AG is an endogenous ligand of cannabinoid receptors, involved in various physiological processes in the brain.
MedKoo Cat#: 522651
Name: SAR629
CAS#: 1221418-42-3
Chemical Formula: C20H19F2N5O
Exact Mass: 383.1558
Molecular Weight: 383.40
Elemental Analysis: C, 62.65; H, 5.00; F, 9.91; N, 18.27; O, 4.17
The following data is based on the product molecular weight 383.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
