NSC659000 | CAS# 139449-81-3

MedKoo Cat#: 407265 | Name: NSC659000

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC659000 is a potential antifungal agent. NSC659000 was first reported in Pharmazie. 1991 Sep;46(9):667-8.

Chemical Structure

NSC659000

CAS# 139449-81-3

Theoretical Analysis

MedKoo Cat#: 407265

Name: NSC659000

CAS#: 139449-81-3

Chemical Formula: C20H13Cl2N3O2

Exact Mass: 397.0385

Molecular Weight: 398.24

Elemental Analysis: C, 60.32; H, 3.29; Cl, 17.80; N, 10.55; O, 8.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NSC659000; NSC-659000; NSC 659000.

IUPAC/Chemical Name

(E)-7-chloro-2-(4-chlorostyryl)-3-(3-methylisoxazol-5-yl)quinazolin-4(3H)-one

InChi Key

JAVHQDGHLLPLMT-RUDMXATFSA-N

InChi Code

InChI=1S/C20H13Cl2N3O2/c1-12-10-19(27-24-12)25-18(9-4-13-2-5-14(21)6-3-13)23-17-11-15(22)7-8-16(17)20(25)26/h2-11H,1H3/b9-4+

SMILES Code

O=C1N(C2=CC(C)=NO2)C(/C=C/C3=CC=C(Cl)C=C3)=NC4=C1C=CC(Cl)=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 398.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Raffa D, Daidone G, Plescia S, Schillaci D. Synthesis and antifungal evaluation of some 3-(3-methyl-5-isoxazolyl)-2-styrylquinazolin-4(3H)-ones. Pharmazie. 1991 Sep;46(9):667-8. PubMed PMID: 1798732.