MedKoo Cat#: 319880 | Name: Velneperit
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Velneperit, also known as S-2367, is potent and selective neuropeptide Y Y5-receptor antagonist under evaluating for treatment of obesity.

Chemical Structure

Velneperit
Velneperit
CAS#342577-38-2

Theoretical Analysis

MedKoo Cat#: 319880

Name: Velneperit

CAS#: 342577-38-2

Chemical Formula: C17H24F3N3O3S

Exact Mass: 407.1490

Molecular Weight: 407.45

Elemental Analysis: C, 50.11; H, 5.94; F, 13.99; N, 10.31; O, 11.78; S, 7.87

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
25g USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
S-2367; S 2367; S2367; Velneperit
IUPAC/Chemical Name
(1r,4r)-4-((1,1-dimethylethyl)sulfonamido)-N-(5-(trifluoromethyl)pyridin-2-yl)cyclohexane-1-carboxamide
InChi Key
WGEWUYACXPEFPO-AULYBMBSSA-N
InChi Code
InChI=1S/C17H24F3N3O3S/c1-16(2,3)27(25,26)23-13-7-4-11(5-8-13)15(24)22-14-9-6-12(10-21-14)17(18,19)20/h6,9-11,13,23H,4-5,7-8H2,1-3H3,(H,21,22,24)/t11-,13-
SMILES Code
O=C([C@H]1CC[C@H](NS(=O)(C(C)(C)C)=O)CC1)NC2=NC=C(C(F)(F)F)C=C2
Appearance
White to off-white solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 407.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bhat SP, Sharma A. Current Drug Targets in Obesity Pharmacotherapy - A Review. Curr Drug Targets. 2017 Feb 27. doi: 10.2174/1389450118666170227153940. [Epub ahead of print] PubMed PMID: 28245771. 2: George M, Rajaram M, Shanmugam E. New and emerging drug molecules against obesity. J Cardiovasc Pharmacol Ther. 2014 Jan;19(1):65-76. doi: 10.1177/1074248413501017. Epub 2013 Sep 24. Review. PubMed PMID: 24064009.