KLS-13019 is a Cannabidiol-Derived Neuroprotective Agent with Improved Potency, Safety, and Permeability. (EC50=40nM; T1=7500). KLS-13019 was 50-fold more potent and >400-fold safer than cannabidiol and exhibited an in vitro profile consistent with improved oral bioavailability. KLS-13019 was only toxic at 300 μM giving it a therapeutic index of 7500.
MedKoo Cat#: 522633
Name: KLS-13019
CAS#: 1801243-39-9
Chemical Formula: C22H29NO3
Exact Mass: 355.2147
Molecular Weight: 355.48
Elemental Analysis: C, 74.33; H, 8.22; N, 3.94; O, 13.50
The following data is based on the product molecular weight 355.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
