Tedalinab, also known GRC-10693, isa potent and selective cannabinoid CB2 receptor agonist under development for the treatment of osteoarthritis and neuropathic pain. It has a very high selectivity of 4700x for CB2 over the related CB1 receptor, has good oral bioavailability and has shown promising safety results and effective analgesic and antiinflammatory actions in early clinical trials.
MedKoo Cat#: 319799
Name: Tedalinab
CAS#: 916591-01-0
Chemical Formula: C19H21F2N3O
Exact Mass: 345.1653
Molecular Weight: 345.39
Elemental Analysis: C, 66.07; H, 6.13; F, 11.00; N, 12.17; O, 4.63
The following data is based on the product molecular weight 345.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |