Trabodenoson, also known as INNO-8875 and PJ 875, is a potent and highly selective adenosine A1 receptor agonist. Trabodenoson was shown to significantly reduce IOP in glaucoma and OHT patients and was well-tolerated. Trabodenoson is the first of a new class of compounds designed to lower IOP with a mechanism of action that augments the natural function of the trabecular meshwork, the main passageway to transport aqueous humor out of the eye.
MedKoo Cat#: 319721
Name: Trabodenoson
CAS#: 871108-05-3
Chemical Formula: C15H20N6O6
Exact Mass: 380.1444
Molecular Weight: 380.36
Elemental Analysis: C, 47.37; H, 5.30; N, 22.10; O, 25.24
The following data is based on the product molecular weight 380.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
