Moexipril is a potent orally active nonsulfhydryl angiotensin converting enzyme inhibitor (ACE inhibitor) which is used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics. It works by inhibiting the conversion of angiotensin I to angiotensin II.
MedKoo Cat#: 319615
Name: Moexipril hydrochloride
CAS#: 82586-52-5 (HCl salt); 103775-10-6 (free base).
Chemical Formula: C27H35ClN2O7
Exact Mass:
Molecular Weight: 535.03
Elemental Analysis: C, 60.61; H, 6.59; Cl, 6.63; N, 5.24; O, 20.93
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 10.0 | 18.69 | |
| DMSO | 100.0 | 186.90 | |
| Ethanol | 25.0 | 46.73 | |
| PBS (pH 7.2) | 0.3 | 0.62 | |
| Water | 100.0 | 186.90 |
The following data is based on the product molecular weight 535.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
