LSPN451 is a potent xanthine oxidase inhibitor. LSPN451 may be potentially useful for the treatment of hyperuricemia and gout. Xanthine oxidase inhibition (XOI) reduces oxidative stress in the vasculature. Moreover it reduces uric acid levels, a risk factor for the development of cardiovascular disease. As such, XOI holds a potentially dual mechanism for the treatment of cardiovascular disease.
MedKoo Cat#: 522589
Name: LSPN451
CAS#: 474555-58-3
Chemical Formula: C13H9N5O4
Exact Mass: 299.0655
Molecular Weight: 299.25
Elemental Analysis: C, 52.18; H, 3.03; N, 23.40; O, 21.39
The following data is based on the product molecular weight 299.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
