SKLB1028 is a novel oral multikinase inhibitor of EGFR, FLT3 and Abl. SKLB1028 displays exceptional activity in models of FLT3-driven AML and considerable potency in models of CML harboring Abl mutants.
MedKoo Cat#: 206574
Name: SKLB-1028
CAS#: 1350544-93-2
Chemical Formula: C24H29N9
Exact Mass: 443.2546
Molecular Weight: 443.56
Elemental Analysis: C, 64.99; H, 6.59; N, 28.42
The following data is based on the product molecular weight 443.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
