MedKoo Cat#: 317513 | Name: Chloroxine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chloroxine is a synthetic antibacterial agent. It inhibits the growth of Gram-positive and some Gram-negative bacteria and also induces SOS-DNA repair. Chlorxine shows bacteriostatic, fungistatic and antiprotozoal effects in vivo.

Chemical Structure

Chloroxine
Chloroxine
CAS#773-76-2

Theoretical Analysis

MedKoo Cat#: 317513

Name: Chloroxine

CAS#: 773-76-2

Chemical Formula: C9H5Cl2NO

Exact Mass: 212.9748

Molecular Weight: 214.05

Elemental Analysis: C, 50.50; H, 2.35; Cl, 33.13; N, 6.54; O, 7.47

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
10g USD 400.00 2 Weeks
25g USD 650.00 2 Weeks
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Related CAS #
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Synonym
Chloroxine; 5,7-Dichloroquinolin-8-ol; 5,7-Dichloro-8-hydroxyquinoline; 773-76-2; Chlorquinol; 5,7-Dichloro-8-quinolinol; chloroxine hydrofluoride; chlorquinol; dichlorohydroxyquinoline; dichloroquine; quixalin;
IUPAC/Chemical Name
5,7-dichloroquinolin-8-ol
InChi Key
WDFKMLRRRCGAKS-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
SMILES Code
C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 214.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Johnson ML. Fluorescence with chloroxine shampoo. Arch Dermatol. 1979 May;115(5):641. PubMed PMID: 443855. 2: Pérez-Ruiz T, Martínez-Lozano C, Tomás V, Carpena J. Fluorimetric determination of chloroxine using manual and flow-injection methods. J Pharm Biomed Anal. 1996 Aug;14(11):1505-11. PubMed PMID: 8877856. 3: Negosanti M, Bettoli V, Valenti R, Patrone P, Celasco G. [Clinical evaluation on the usefulness of 5,7-dichloro-8-hydroxyquinoline (chloroxine) in association with betamethasone 17-benzoate in the topical treatment of infected cortisone-sensitive dermopathies]. G Ital Dermatol Venereol. 1985 Mar-Apr;120(2):XVII-XXIII. Italian. PubMed PMID: 4007946. 4: Stocchi F. [Clinical tests of topical preparations containing betamethasone 17-benzoate and the same associated with 5,7-dichloro-8-hydroxyquinoline (chloroxine)]. Clin Ter. 1977 Nov 30;83(4):359-69. Italian. PubMed PMID: 603986. 5: Chládek S, Zemlicka J, Gut V. 5-chloro-8-hydroxyquinoline (chloroxine) esters of carboxylic acid--selective reagents for acylation of nucleoside and nucleotide aminoacyl derivatives. Biochem Biophys Res Commun. 1969 Apr 29;35(2):306-11. PubMed PMID: 5772585.